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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
35.15
Human Site:
T253
Identified Species:
55.24
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
T253
I
G
Q
Y
G
G
E
T
V
K
I
V
R
I
E
Chimpanzee
Pan troglodytes
XP_510014
764
85553
T342
I
G
Q
Y
G
G
E
T
V
K
I
V
R
I
E
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
T252
I
G
Q
Y
G
G
E
T
V
K
I
V
R
I
E
Dog
Lupus familis
XP_547862
675
77214
T253
I
G
Q
Y
G
G
E
T
V
K
I
V
R
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
T253
I
G
H
Y
G
G
E
T
V
K
I
V
R
I
E
Rat
Rattus norvegicus
Q5U2Y3
576
65604
P218
A
I
T
F
K
I
I
P
S
T
K
E
E
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
T253
V
G
Q
Y
G
G
E
T
V
K
I
V
R
I
E
Chicken
Gallus gallus
Q5ZJ00
468
52501
L113
M
I
H
R
Q
G
S
L
H
V
G
D
E
I
I
Frog
Xenopus laevis
NP_001085267
675
76810
T253
I
G
L
Y
G
D
E
T
V
K
I
V
R
I
D
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
T255
L
T
Q
W
G
G
E
T
V
K
I
V
R
I
E
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
S112
G
M
I
H
R
Q
G
S
L
H
E
G
D
E
I
Fruit Fly
Dros. melanogaster
Q24210
898
100893
H489
V
E
G
G
E
L
Q
H
V
T
R
V
R
L
V
Honey Bee
Apis mellifera
XP_393395
1033
115664
N592
R
G
S
R
V
V
D
N
I
K
I
I
R
I
E
Nematode Worm
Caenorhab. elegans
P54936
961
108794
K433
V
D
T
S
T
L
R
K
E
T
L
N
Q
I
D
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
S548
L
P
E
D
G
E
E
S
V
K
I
V
R
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
93.3
13.3
80
80
0
20
40
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
100
20
86.6
93.3
20
40
60
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
7
7
0
0
0
0
7
7
0
14
% D
% Glu:
0
7
7
0
7
7
60
0
7
0
7
7
14
7
60
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
54
7
7
60
54
7
0
0
0
7
7
0
0
0
% G
% His:
0
0
14
7
0
0
0
7
7
7
0
0
0
0
0
% H
% Ile:
40
14
7
0
0
7
7
0
7
0
67
7
0
87
14
% I
% Lys:
0
0
0
0
7
0
0
7
0
67
7
0
0
0
0
% K
% Leu:
14
0
7
0
0
14
0
7
7
0
7
0
0
7
0
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
7
% P
% Gln:
0
0
40
0
7
7
7
0
0
0
0
0
7
0
0
% Q
% Arg:
7
0
0
14
7
0
7
0
0
0
7
0
74
0
0
% R
% Ser:
0
0
7
7
0
0
7
14
7
0
0
0
0
0
0
% S
% Thr:
0
7
14
0
7
0
0
54
0
20
0
0
0
0
0
% T
% Val:
20
0
0
0
7
7
0
0
67
7
0
67
0
0
7
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _